Searchable abstracts of presentations at key conferences in endocrinology

ea0033p20 | (1) | BSPED2013

18F-DOPA PET and enhanced CT imaging for congenital hyperinsulinism: Our experience of using oral sedation

Shah Pratik , Senniappan Senthil , du Preez Marguerite , Endozo Raymond , Townsend Caroline , Gilbert Clare , Morgan Kate , Hinchey Louise , Pierro Agostino , Biassoni Lorenzo , Olsen Oystein , Bomanji Jamshed , Hussain Khalid

Introduction: Congenital hyperinsulinism (CHI) is the most common cause of persistent hypoglycaemia in infants and children. Histologically there are two subgroups, diffuse and focal. Fluorine-18-L dihydroxyphenylalanine positron emission tomography (18F-DOPA PET/CT) helps to differentiate focal from diffuse CHI.Objective and hypotheses: To evaluate the feasibility of using 18F-DOPA PET/CT for the diagnosis of focal or diffuse CHI u...

ea0033p15 | (1) | BSPED2013

18F-DOPA PET MRI as a new imaging modality for the precise localisation of focal congenital hyperinsulinism

Senniappan Senthil , Shah Pratik , du Preez Marguerite , Endozo Raymond , O'Meara Celia , Townsend Caroline , Gilbert Clare , Morgan Kate , Hinchey Louise , Pierro Agostino , Biassoni Lorenzo , Olsen Oystein , Bomanji Jamshed , Hussain Khalid

Introduction: Congenital hyperinsulinism (CHI) includes two major histological subtypes; diffuse and focal. Fluorine-18-L dihydroxyphenylalanine positron emission tomography (18F-DOPA PET/CT) has been established as a novel imagining technique to differentiate focal from diffuse CHI. However CT provides only limited soft tissue contrast and exposes the patient to a significant radiation dose. PET/MRI could provide images with an excellent soft tissue contrast, very ...